WebJan 31, 2024 · OTUB2 is upregulated in liver cancer cell lines, and knockdown of OTUB2 inhibits liver cancer cell growth. A, Liver cell lines were prepared for qRT-PCR against OTUB2. B, Huh7 and SNU-387 cells were infected with shNC, shOTUB2#1, or shOTUB2#2 lentivirus for 72 hours, followed by qRT-PCR against OTUB2. WebCell lines with the highest expression of OTUB2 were transfected with lentivirus to knockdown OTUB2 levels. Changes in KYSE150 cell proliferation, migration, and …

OTUB2 regulates KRT80 stability via deubiquitination and

WebJan 1, 2024 · In NSCLC cell lines, OTUB2 promoted cell growth, colony formation, migration, and invasive activities. Mechanistic investigations showed that OTUB2 stimulated the Warburg effect and induced the activation of the serine/threonine kinase/mechanistic target of rapamycin kinase (AKT/mTOR) pathway in different NSCLC cells. WebMar 29, 2024 · OTUB2 is a novel promoter of viability and insulin secretion in human beta cells. OTUB2 acts through the inhibition of NF-kappaB signalling. Findings suggest that … lowe\u0027s carpet and flooring

OTUB2 protein (His tag) - 其他重组蛋白 - 深圳欣博盛生物科技有 …

WebOTUB2 Introduction The Anti-OTUB2 (CB-P62) h (scFv-CD28TM-CD79β) CBCR (CAR-B) vector is composed of an anti-OTUB2 antibody-based binding domain, which is fused with the CD79β signaling domain, a component of the B cell receptor (BCR) complex that is responsible for activation. WebFeb 2, 2024 · We found that AGS cells show high KRT80 and OTUB2 expression and that MKN45 cells show low KRT80 expression, although the expression of OTUB2 and … WebMar 2, 2024 · OTUB2 is involved in the deubiquitination of many key proteins in different cell signaling pathways, and the effect of OTUB2 on human health or disease is not clear. OTUB2 is likely to cause cancer and other malignant diseases while maintaining normal … lowe\u0027s carpet deals