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Gpx4 antibody cst

WebDec 31, 2024 · Glutathione peroxidase 4 (GPX4)-dependent ferroptosis in pancreatic acinar cells plays a critical role in acute pancreatitis (AP). However, potential upstream regulators of GPX4 are not well defined. Here, we observed a marked reduction in acinar GPX4 expression and ferroptotic cell death in mice with cerulein-induced AP. To determine the … WebNov 12, 2024 · CST1 relieves GPX4 ubiquitination modification by recruiting OTUB1, improving GPX4 protein stability and reducing intracellular reactive oxygen species (ROS), thereby inhibiting ferroptosis...

GPX4 Antibody Cell Signaling Technology

WebThis antibody is predicted to react with many species based on sequence homology. Target Information Glutathione peroxidase catalyzes the reduction of hydrogen peroxide, organic hydroperoxide, and lipid … WebThe selenoprotein glutathione peroxidase 4 (GPX4) is a master regulator of ferroptosis, a form of programmed cell death induced by iron-dependent lipid peroxidation (1,2). GPX4 … phoneshoppy.com https://eurekaferramenta.com

Anti-GPX4 Polyclonal Antibody_一抗_抗体_索莱宝-专业生化试剂 …

WebJul 15, 2024 · Primary antibodies against GPX4 (Abcam, ab125066) and GAPDH (CST, 5174) and secondary antibodies against rabbit IgG (CST, 7074) and mouse IgG (CST, … WebProteintech Anti-GPX4 Polyclonal, Catalog # 14432-1-AP. Tested in Western Blot (WB) and Immunoprecipitation (IP) applications. This antibody reacts with Human, Mouse, Rat … WebGPX4 Antibody recognizes endogenous levels of total GPX4 protein. Species Reactivity: Human, Mouse, Monkey Source / Purification Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues near the carboxy terminus of human GPX4 protein. Antibodies are purified by peptide affinity … how do you store fresh figs

Anti-Glutathione Peroxidase 4 antibody (ab41787) - Abcam

Category:GPX4 Antibody Cell Signaling Technology

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Gpx4 antibody cst

Antioxidants Free Full-Text Identification of AP-1 as a Critical ...

WebPolyclonal Antibody for studying GPX4. Cited in 8 publications. Validated for Western Blotting. Highly specific and rigorously validated in-house, GPX4 Antibody (CST … WebBoth ACSL4 and GPX4 were expressed mainly in the cytoplasm and occasionally in the interstitial of breast cancer cells. The representative IHC staining images are shown in Fig. 1. The mean density of ACSL4 and GPX4 was 0.092 ± 0.070 (range, 0.002–0.370) and 0.092 ± 0.072 (range, 0.003–0.436), respectively .

Gpx4 antibody cst

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WebGPX4 antibody 14432-1-AP is a primary antibody from Proteintech 78 Citations Host: Rabbit Clonality: Polyclonal Validations: None Available Applications: WB, IHC and 3 more Reactivity: Homo sapiens (Human), Mus musculus (House mouse) and 2 more Anti-Glutathione Peroxidase 4 antibody ab41787 is a primary antibody from Abcam 41 … WebGPX4 (Phospholipid hydroperoxide glutathione peroxidase, mitochondrial) protects cells against membrane lipid peroxidation and cell death. Required for normal sperm development and male fertility.It has two isforms about …

WebJan 20, 2024 · Here, we firstly reveal that GPX4 regulated mitochondria-mediated apoptosis through regulation of EGR1 in TNBC cells. Compound 13, the prodrug of DMOCPTL, effectively inhibited the growth of breast tumor and prolonged the lifespan of mice in vivo, and no obvious toxicity was observed. Conclusions WebWild-type HeLa and GPX4 knockout cell lysates were subjected to SDS-PAGE. Membranes were blocked in 3 % milk in TBS-T (0.1 % Tween ® ) before incubation with ab125066 …

WebAnti-GPX4 Polyclonal Antibody 交叉反应: Human,Rat,Mouse. 应用: WB 克隆类型: Polyclonal Antibody. 保存: Store at -20℃. Avoid freeze / thaw cycles. 宿主: Rabbit. 说明书下载 Anti-GPX4 Polyclonal Antibody. 货号: K113159P ... WebJul 22, 2014 · Intracellular localization of butyrate-induced GPx4 expression in VSMC. VSMC untreated (A) or treated (B) with 5 mM butyrate for different periods of time were processed for immunostaining of GPx4 with an antibody specific to GPx4 followed by Alexa flour 488 conjugated second antibody, as described in the Experimental Section. (400× ...

WebGlutathione peroxidase 4 (GPX4) is a selenocysteine-containing glutathione peroxidase that is encoded by the GPX4 gene in humans and protects cellular membranes from oxidative damage.1,2 It is a monomeric protein consisting of a thioredoxin motif and a selenocysteine-glutamine-tryptophan catalytic triad that reduces lipid hydroperoxides ...

WebSep 1, 2015 · GPx4 was visualized in whole zebrafish embryos by indirect immunofluorescence using a primary antibody against C-terminus of human GPx4 (Schoenmakers et al., 2010, Huang et al., 2009).This antibody could potentially recognize both predicted zebrafish GPx4 proteins a and b because the amino acid sequence of the … how do you store fresh dillWebGPX4 Antibody (PA5-18545) in IHC (P) Immunohistochemical staining of paraffin embedded of Human Testis using Product # PA5-18545 at a concentration of 0.3 µg/mL. The tissue was processed by microwaved … how do you store fruits in gpoWebApr 12, 2024 · Anti-FAP antibody was selected from a naïve scFv phage library. Then the antibody was converted into scFv-Fc format, transiently expressed by 293F cells and purified using protein A affinity chromatography. ... (CST), anti-CD4 (Abcam) and anti-CD8α (Abcam). Briefly, the sections were exposed to 3% H 2 O 2 in methanol after … how do you store fresh cilantroWebOct 25, 2024 · GPx-4 Antibody (E-12) is available as both the non-conjugated anti-GPx-4 antibody form, as well as multiple conjugated forms of anti-GPx-4 antibody, including agarose, HRP, PE, FITC and multiple … phoneslabWebNov 12, 2024 · CST1 interacts with GPX4 to improve the stability of the GPX4 protein To investigate the mechanism underlying the CST1 in GC cells, we analyzed MKN45 cells by immunoprecipitation (IP) assay... how do you store fresh herbs after buyinghow do you store fresh gingerWebRabbit GPX4 Rabbit pAb (A13309), validaed in WB,IF/ICC and tested in Human,, Mouse,, Rat. 100% Guaranteed. ABclonal provides free trial antibodies for target detection. … how do you store fresh herbs