Dynein cytoplasmic 1 heavy chain 1
WebNov 2, 2010 · Cytoplasmic dynein 2 heavy chain 1. Alternative names. Cytoplasmic dynein 2 heavy chain; Dynein cytoplasmic heavy chain 2; Dynein heavy chain 11 (hDHC11) Dynein heavy chain isotype 1B; Gene names. Name. DYNC2H1. Synonyms. DHC1B, DHC2, DNCH2, DYH1B, KIAA1997. Organism names. Organism. Homo … WebMay 11, 2024 · Dynein Cytoplasmic 1 Heavy Chain 1 (DYNC1H1) is a protein coding gene which encodes the cytoplasmic dynein heavy chain family. This is the first investigation into the expression of DYNC1H1 and its mechanisms of action in LIHC patients. Methods: Based on the DYNC1H1 expression data from the TCGA database, we performed the …
Dynein cytoplasmic 1 heavy chain 1
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WebSep 25, 2013 · The cytoplasmic dynein 1 heavy chain (encoded by DYNC1H1 in humans) is used for nearly all of the minus end-directed transport in the cytoplasm of most eukaryotic cells . WebMay 11, 2024 · Dynein Cytoplasmic 1 Heavy Chain 1 (DYNC1H1) is a protein coding gene which encodes the cytoplasmic dynein heavy chain family. This is the first …
WebDec 8, 2024 · Figure 1. A schematic diagram of cytoplasmic dynein protein complex. (a) Cytoplasmic dynein is a protein complex consisting of two homodimerized heavy chains (DYNC1H1) and associated proteins … WebJan 4, 2005 · The cytoplasmic dynein 1 complex consists of two catalytic heavy chains (HCs) and a number of non-catalytic subunits presented by intermediate chains (ICs), …
WebJan 27, 2006 · DYNC1H1, cytoplasmic dynein 1 heavy chain 1, is the largest cytoplasmic dynein subunit, having ~4,600 residues and a molecular weight of >530 kDa. First identified in rat spinal cord and brain and termed Microtubule Associated Protein 1C (MAP1C) [ 24 ], DYNC1H1 is a distant member of the AAA family of ATPases and is the … WebMar 23, 2006 · The library was examined for inhibition of cytoplasmic dynein heavy chain and cell growth. The compounds showed effective antiproliferative activity against a mouse leukemia cell line but selective activities against human carcinoma cell lines. Purealin and some of the analogues inhibited the microtubule-stimulated ATPase activity of ...
WebCytoplasmic dynein 2 heavy chain 1. Alternative names. Cytoplasmic dynein 2 heavy chain; Dynein cytoplasmic heavy chain 2; Dynein heavy chain isotype 1B; Dynein-like protein 4; Gene names. Name. Dync2h1. Synonyms. Dhc1b, Dlp4, Dnch2, Dnchc2. Organism names. Organism. Rattus norvegicus (Rat) Taxonomic identifier.
WebMar 27, 2024 · Introduction. Cytoplasmic dynein 1 (dynein) is a microtubule (MT) motor protein complex that is responsible for retrograde transport of cellular cargos such as proteins, RNAs, and organelles 1, 2.Dynein is composed of four subunit classes: the heavy chain (HC), light intermediate chain (LIC), intermediate chain (IC), and light chain (LC) … northlab photonicsWebFeb 26, 2024 · Dynein, one of three cytoskeletal motor protein families, was first identified a half century ago and got its name after the ‘dyne’ (i.e. a unit of force). Motor proteins are … north labelWebJun 26, 2011 · 1 Introduction. Cytoplasmic dynein is a microtubule (MT) motor protein that is involved in various activities within eukaryotic cells. Cytoplasmic dynein comprises two classes: dynein-1 and dynein-2 [].Cytoplasmic dynein-1 is a minus-end-directed MT motor protein that moves by the energy derived from ATP hydrolysis [], and is involved in … north labs llcWebBackground: The DYNC1H1 gene encodes the heavy chain of cytoplasmic dynein 1, a core structure of the cytoplasmic dynein complex. Dominant DYNC1H1 mutations are implicated in Charcot-Marie-Tooth disease, axonal, type 20, spinal muscular atrophy, lower extremity-predominant 1, and autosomal dominant mental retardation 13 with neuronal … northlab seams pte ltdWebFeb 14, 2024 · Mutations in the gene encoding the heavy chain of the cytoplasmic dynein-1 (dynein) motor have repeatedly been implicated in neurological diseases … how to say methuselahWebJul 4, 2016 · Expression of dynein, cytoplasmic 2, heavy chain 1 (DHC2) associated with glioblastoma cell resistance to temozolomide Sci Rep. 2016 Jul 4; 6:28948. ... 1 Department of Neurosurgery, Nanfang Glioma Center, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China. how to say metonymyWebJan 20, 2024 · Cytoplasmic dyneins lack the additional LC8 paralogs and have either one (dynein-1) or three copies (dynein-2) of the LC8 homodimer (Fig. 3c, d). Thus, axonemal and cytoplasmic dyneins have ... how to say me too in asl