WebDec 22, 2024 · (A–E) The levels of BIP, ATF6, p-PERK and c-fos increase in the ipsilateral lumbar enlargement of the spinal cord in the formalin group compared to the control group, 1 hour after injection of 50 μL of 5% formalin. Intraperitoneal injection of 4-PBA at 30 minutes before formalin injection inhibits the expression of BIP, ATF6, p-PERK and c ... Web(A–E) The levels of BIP, ATF6, p-PERK and c-fos increase in the ipsilateral lumbar enlargement of the spinal cord in the formalin group compared to the control group, 1 hour after injection of 50 μL of 5% formalin. Intraperitoneal injection of 4-PBA at 30 minutes before formalin injection inhibits the expression of BIP, ATF6, p-PERK and c ...
A lifetime of stress: ATF6 in development and homeostasis
WebJul 1, 2002 · A study by Shen et al. (2002), in this issue of Developmental Cell shows that transport to the Golgi complex and subsequent proteolytic activation of the stress … WebAug 6, 2024 · Quantitation of BiP-bound ATF6 levels in ATF6 immunoprecipitates is shown (graph). The mean ± SD of three independent experiments is shown. (D) ATF6 is glycosylated to a similar extent after activation by either Tg, DTT, DHC, or DHS. HEK293 cells were treated with Tg, DHS, DHC, or DTT for 2 hr, before ATF6 was … dickinson park wyoming
ATF6抑制剂和其用途【掌桥专利】
WebFigure S1D. Expression of BiP and GRP94 in H2.35 Cells Overexpressing CREBH or ATF6 H2.35 cells in a 35 mm collagen-coated plate were transfected with 1.5 µg empty DNA vector, vector expressing the nuclear form of CREBH (CREBH-N) or vector expressing the nuclear form of ATF6 (ATF6 p50), respectively. Expression levels of BiP and GRP94 WebFeb 21, 2024 · We also found that UPR-related genes, namely BIP, ATF6 and, albeit to a lower extent, CHOP are less expressed in GI compared to NG obese patients. This may be related to the higher amount of BIP protein since BIP buffering capacity on IRE1, PERK and ATF6 may reduce their activation, ... WebSep 24, 2024 · Consistent with prior studies, treatment of HEK293 cells expressing the Class 1 ATF6 disease-associated proteins with the chemical ER stressor, dithiothreitol … citrix probe enumeration failure reasons